2025 Silent Capital Report now available. Where family offices and LPs are actually deploying. [Download for free →]
About usSign in
Status
ACTIVE
Global HQ
Palo Alto, United States
Countries of investment
  • United States
Investment stages
  • Series A
  • Series B
  • Series C
  • Growth
  • IPO
Industries
  • Biotechnology
  • Life Sciences
  • Pharma
  • Biologics
About
TCG Crossover (TCGX) is a science-driven investment firm dedicated to advancing disruptive and breakthrough medicines. They support innovative biotechnology companies, offering deep domain expertise and capital to steer advanced therapeutic concepts from development into reality. Their mission is to enable extraordinary continuations in healthcare by funding the technologies that shape next-generation patient treatment.
Min check size
$10M
Max check size
$50M
Fund size
NPS

Investment Thesis

TCG Crossover (TCGX) is a science-driven healthcare investment firm that backs both private and public biotechnology companies globally. Their core thesis states that hard science drives fiscal returns, deploying capital into novel pre-IPO and public therapeutics addressing high unmet medical needs like advanced oncology. What makes TCGX unique is its specialized position as a dedicated crossover vehicle born out of The Column Group ecosystem, which provides companies with an elite, molecular-level technical network capable of guiding clinical assets straight through complex big-pharma M&A or public market listings.
Lead investor
Co Invest
Number of exits
Preferred contact method

Manager's Experience

Founded in 2021 by Chen Yu, a former Managing Partner at Vivo Capital with over 20 years in public and private life sciences investing. TCGX has raised $3.1B in total, with exits including Tourmaline Bio's $1.4B sale to Novartis and ADARx's IPO.

TCG Crossover Contacts Information

Primary contact

Secondary contact

Team

Chen Yu - Founder & Managing Partner

Giuliano Marostica - Managing Partner

Cariad Chester - Managing Partner

Dandan Dong - Managing Partner Asia

Craig Skaling - CFO & COO

Portfolio

Candid Therapeutics

Tourmaline Bio

Adcendo

ADARx Pharmaceuticals

Fund number
Year Founded
Vintage Year
Net Internal Rate of Return
Investment Multiple
Capital Allocation
Management Fee
Carried Interest
AUM
Follow-on Investments
Graduation Rate
Write-Off Ratio
Last profile update timestamp