2025 Silent Capital Report now available. Where family offices and LPs are actually deploying. [Download for free →]
About usSign in
Status
ACTIVE
Global HQ
San Francisco, United States
Countries of investment
  • United States
  • United Kingdom
Investment stages
  • Seed
  • Series A
Industries
  • Biotech
  • Healthcare
About
SR One is a leading biotechnology venture capital firm that invests in visionary entrepreneurs and groundbreaking science. Founded in 1985 as the venture arm of GSK and now an independent firm, they partner with companies to develop and commercialize novel medicines and healthcare technologies.
Min check size
$2M
Max check size
$20M
Fund size
NPS

Investment Thesis

SR One is a transatlantic biotech venture capital firm focused on building elite biotechnology companies that translate innovative science into meaningful patient impact. As the former corporate venture arm of GSK, they leverage deep scientific and operational expertise to invest in both early-stage and growth-stage opportunities. Their unique value proposition stems from their long-standing industry presence, extensive network, and hands-on approach to company building, from discovery through commercialization.
Lead investor
Co Invest
Number of exits
Preferred contact method

Manager's Experience

The managing partners, Simeon J. George, M.D., and Matthew Foy, Ph.D., co-led the firm's spin-out from GSK and have decades of combined experience in life sciences venture capital. Their backgrounds blend deep scientific expertise with extensive operational and investment history, having served on the boards of over 20 private and public companies each. The team's core focus is on building elite biotechnology companies from early stages.

SR One Capital Management Contacts Information

Primary contact

Secondary contact

Team

Simeon George - Managing Partner

Rajeev Dadoo - Managing Partner

Matthew Foy - Managing Partner

Jill Carroll - Partner & COO

Rodger Novak - Venture Partner

Eliot Charles - Venture Partner

Oleg Nodelman - Venture Partner

Shaan C. Gandhi - Principal

Portfolio

CRISPR Therapeutics

Arcellx

Nkarta

Alchemab

ApcinteX

Atopix Therapeutics

Adcendo

Alector

Principia Biopharma

Turning Point Therapeutics

Sutro Biopharma

Fund number
Vintage Year
Net Internal Rate of Return
Investment Multiple
Capital Allocation
Management Fee
Carried Interest
AUM
Follow-on Investments
Graduation Rate
Write-Off Ratio
Last profile update timestamp