Main Sequence Ventures Fund III

Main Sequence Ventures

Status

ACTIVE

Global HQ

Sydney, Australia

Countries of investment

Australia
New Zealand
United States
United Kingdom

Investment stages

Pre-Seed
Seed
Series A
Series B

Industries

Space
Food
Industry
Health
Sustainability
DeepTech
Advanced Manufacturing
Biotech
AI
Quantum

About
Main Sequence is a Sydney-based venture capital firm focused on backing deep tech founders addressing humanity's greatest challenges. Their focus spans space, food, industry, health, and sustainability across Australia, New Zealand, United States, and United Kingdom. The firm supports deep tech founders from pre-seed through Series B stages.

Min check size: $1M
Max check size: $10M
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Investment Thesis

Main Sequence is a pre-seed to Series B stage venture capital firm deploying capital across space, food, industry, health, and sustainability sectors. They invest in deep tech companies solving humanity's biggest challenges, with strong ties to CSIRO (Australia's national science agency) providing access to research and IP. The firm differentiates itself as Australia's national deep tech investor, backed by CSIRO, with $1B+ AUM across three funds and unique access to Australian scientific research infrastructure.

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Manager's Experience

Founded in 2017 as CSIRO's dedicated venture capital fund, led by Bill Bartee (Managing Partner and Co-founder), Mike Zimmerman (Managing Partner and Co-founder, former partner at Blackbird Ventures), Phil Morle (Partner, co-founder of Pollenizer and executive at Amazon Studios), and Martin Duursma (Partner, former Vice President and Chief Scientist at Citrix). Team of 15+ investment professionals operating from Sydney with additional presence across Australia. Manages three funds totaling over $1B AUD in AUM. Backed by CSIRO (Australia's national science agency), Australian Government, and institutional investors. Portfolio of 60+ deep tech companies including Q-CTRL (quantum computing), Vow (cultivated meat), Samsara Eco (plastic recycling), Cortical Labs (biological computing), Advanced Navigation, and Loam Bio. Provides portfolio companies with unique access to CSIRO's research capabilities, IP, and scientific infrastructure.