2025 Silent Capital Report now available. Where family offices and LPs are actually deploying. [Download for free →]
About usSign in
Status
ACTIVE
Global HQ
San Francisco, United States
Countries of investment
  • United States
Investment stages
  • Seed
  • Series A
Industries
  • Software
  • Artificial Intelligence
  • Enterprise SaaS
  • Fintech
  • Cybersecurity
  • Consumer
  • Developer Tools
  • Infrastructure
  • B2B
About
Chemistry VC is a San Francisco-based venture capital firm focused on leading investments in early-stage software companies. Their focus spans software, AI, enterprise SaaS, fintech, cybersecurity, and consumer across the United States. The firm supports software founders from seed through Series A stages.
Min check size
$2M
Max check size
$10M
Fund size
NPS

Investment Thesis

Chemistry VC is a seed and Series A stage venture capital firm deploying capital across software, AI, enterprise SaaS, fintech, cybersecurity, and consumer sectors. They lead investments in software companies with high conviction check sizes at seed and Series A stages, operating with a lean investment team of experienced partners. The firm differentiates itself through the collective experience of founding partners who previously invested at Bessemer, USV, and Homebrew, bringing decades of software investing expertise and hands-on founder support.
Lead investor
Co Invest
Number of exits
Preferred contact method

Manager's Experience

Co-founded in 2024 by three highly experienced venture capitalists: Ethan Kurzweil (Founder and Managing Partner, 16 years at Bessemer Venture Partners where he led investments in PagerDuty, Intercom, SendGrid, and Twitch), Mark Goldberg (Managing Partner, formerly Partner at Index Ventures where he invested in Plaid and Bridge, previously led Business Strategy & Operations at Dropbox), and Kristina Shen (Managing Partner, formerly General Partner at Andreessen Horowitz and Bessemer where she backed Sprig and Decagon). The three founding partners' combined portfolio includes investments in Plaid, Twitch, Sprig, Decagon, PagerDuty, Intercom, and SendGrid. The firm raised a $350M debut fund in 2024, oversubscribed and focused on hands-on Series A and seed investments. Chemistry writes $3M-$30M checks with an average of $10M-$12M for Series A investments, planning just 2-3 investments per partner annually to maintain founder-first attention.

Chemistry VC Contacts Information

Primary contact

Secondary contact

Team

Ethan Kurzweil - Founder & Managing Partner

Mark Goldberg - Managing Partner

Kristina Shen - Managing Partner

Portfolio

Assort Health

Alix

plus additional stealth Series A investments (24 total tracked investments)

Fund number
Vintage Year
Net Internal Rate of Return
Investment Multiple
Capital Allocation
Management Fee
Carried Interest
AUM
Follow-on Investments
Graduation Rate
Write-Off Ratio
Last profile update timestamp